Potent dCTPase pyrophosphatase 1 inhibitor (IC50 = 47 nM).
TH 1217 is not stable in aqueous solution. It is recommended that fresh samples are prepared and used immediately.
Sold under license from Thomas Helleday's Foundation for Medical Research and Oxcia AB.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 491.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.04 mL||10.18 mL||20.36 mL|
|5 mM||0.41 mL||2.04 mL||4.07 mL|
|10 mM||0.2 mL||1.02 mL||2.04 mL|
|50 mM||0.04 mL||0.2 mL||0.41 mL|
References are publications that support the biological activity of the product.
Llona-Minguez et al (2016) Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1. J.Med.Chem. 59 1140 PMID: 26771665
If you know of a relevant reference for TH 1217, please let us know.
View Related Products by Product Action
Keywords: TH 1217, TH 1217 supplier, TH1217, XTP3TPA, dCTP1, pyrophosphatase, diphosphatase, 1, inhibitors, inhibits, potent, nucleotidohydrolase, Other, Hydrolases, 6522, Tocris Bioscience
Citations for TH 1217
Citations are publications that use Tocris products.
Currently there are no citations for TH 1217. Do you know of a great paper that uses TH 1217 from Tocris? Please let us know.
Reviews for TH 1217
There are currently no reviews for this product. Be the first to review TH 1217 and earn rewards!
Have you used TH 1217?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)New
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells