You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Toll-like receptor (TLR) 5/Flagellin complex antagonist (IC50 = 0.85 μM). Competes with flagellin for TLR5 binding to inhibit the TLR5:flagellin interaction and subsequent downstream TNF-α secretion.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||2.27||5 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 453.54. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.05 mM||44.1 mL||220.49 mL||440.98 mL|
|0.25 mM||8.82 mL||44.1 mL||88.2 mL|
|0.5 mM||4.41 mL||22.05 mL||44.1 mL|
|2.5 mM||0.88 mL||4.41 mL||8.82 mL|
References are publications that support the biological activity of the product.
Yan et al (2016) Pyrimidine triazole thioether derivatives as toll-like receptor 5 (TLR5)/flagellin complex inhibitors. Chem.Med.Chem. 11 822 PMID: 26634412
If you know of a relevant reference for TH 1020, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TH 1020, TH 1020 supplier, TH1020, Toll, like, receptor, flagellin, complex, TLR5, TNFalpha, TNFa, TNFα, Toll-like, Receptors, 6191, Tocris Bioscience
Citations for TH 1020
Citations are publications that use Tocris products.
Currently there are no citations for TH 1020. Do you know of a great paper that uses TH 1020 from Tocris? Please let us know.
Reviews for TH 1020
There are currently no reviews for this product. Be the first to review TH 1020 and earn rewards!
Have you used TH 1020?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.