TCS 3035

Pricing Availability Delivery Time Qty
Cat.No. 4244 - TCS 3035 | C12H9NO5S | CAS No. 871085-49-3
Description: GPR35 agonist
Chemical Name: 2-[4-[(Z)-(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxyacetic acid
Purity: ≥98% (HPLC)

Biological Activity

GPR35 agonist (pEC50 values are 5.13 and 5.86 for rat and human GPR35 orthologs, respectively).

Compound Libraries

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Technical Data

M. Wt 279.27
Formula C12H9NO5S
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 871085-49-3
PubChem ID 2295463
Smiles O=C(/C(S2)=C/C1=CC=C(OCC(O)=O)C=C1)NC2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 27.93 100
ethanol 2.79 10mM with sonication

Preparing Stock Solutions

The following data is based on the product molecular weight 279.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.58 mL 17.9 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL
10 mM 0.36 mL 1.79 mL 3.58 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Jenkins et al (2011) Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2. Br.J.Pharmacol. 162 733 PMID: 20958291

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Keywords: TCS 3035, supplier, TCS3035, GPR35, G-protein, coupled, receptors, agonists, GPR35, GPR35, Tocris Bioscience

Citations for TCS 3035

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Literature in this Area


GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling

Pathways for TCS 3035


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