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Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM). Exhibits 20-fold and 80-fold selectivity for ENT4 over ENT2 and ENT1, respectively.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 504.71. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||9.91 mL||49.53 mL||99.07 mL|
|1 mM||1.98 mL||9.91 mL||19.81 mL|
|2 mM||0.99 mL||4.95 mL||9.91 mL|
|10 mM||0.2 mL||0.99 mL||1.98 mL|
References are publications that support the biological activity of the product.
Wang et al (2013) Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochem.Pharmacol. 86 1531 PMID: 24021350
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Keywords: TC-T 6000, TC-T 6000 supplier, potent, selective, ENT4, inhibitors, inhibits, equilibrative, nucleoside, transporter, 4, Nucleoside, Transporters, 5100, Tocris Bioscience
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