TC-T 6000

Discontinued Product

TC-T 6000 (Cat. No. 5100) has been withdrawn from sale for commercial reasons.
Cat.No. 5100 - TC-T 6000 | C26H48N8O2 | CAS No. 949467-71-4
Description: Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor
Chemical Name: 2,2'-[[4,8-Bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis-ethanol
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews

Biological Activity for TC-T 6000

Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM). Exhibits 20-fold and 80-fold selectivity for ENT4 over ENT2 and ENT1, respectively.

Technical Data for TC-T 6000

M. Wt 504.71
Formula C26H48N8O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 949467-71-4
PubChem ID 16757265
InChI Key KIZLZYHFIWWKIL-UHFFFAOYSA-N
Smiles CC(C)CN(CC(C)C)C2=NC(NCCO)=NC1=C(N(CC(C)C)CC(C)C)N=C(NCCO)N=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for TC-T 6000

References are publications that support the biological activity of the product.

Wang et al (2013) Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochem.Pharmacol. 86 1531 PMID: 24021350

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Keywords: TC-T 6000, TC-T 6000 supplier, potent, selective, ENT4, inhibitors, inhibits, equilibrative, nucleoside, transporter, 4, Nucleoside, Transporters, 5100, Tocris Bioscience

Citations for TC-T 6000

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