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Biological Activity for TC-O 9311
TC-O 9311 is a potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.
Compound Libraries for TC-O 9311
Technical Data for TC-O 9311
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for TC-O 9311
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for TC-O 9311
The following data is based on the product molecular weight 365.38. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.47 mL||27.37 mL||54.74 mL|
|2.5 mM||1.09 mL||5.47 mL||10.95 mL|
|5 mM||0.55 mL||2.74 mL||5.47 mL|
|25 mM||0.11 mL||0.55 mL||1.09 mL|
References for TC-O 9311
References are publications that support the biological activity of the product.
Shi et al (2011) Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139. ACS Med.Chem.Lett. 2 303
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Keywords: TC-O 9311, TC-O 9311 supplier, TCO9311, gpr139, receptors, orphan, potent, selective, agonists, Orphan, 7-TM, Receptors, 4255, Tocris Bioscience
1 Citation for TC-O 9311
Citations are publications that use Tocris products. Selected citations for TC-O 9311 include:
Nepomuceno et al (2018) Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol 9 157 PMID: 29599718
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Literature in this Area
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