TC-O 9311

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Cat.No. 4255 - TC-O 9311 | C20H19N3O4 | CAS No. 444932-31-4
Description: Potent and selective GPR139 agonist
Chemical Name: 3,5-Dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.

Compound Libraries

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Technical Data

M. Wt 365.38
Formula C20H19N3O4
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 444932-31-4
PubChem ID 3376937
InChI Key KPTMSQHTGZMEFU-UHFFFAOYSA-N
Smiles O=C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)C1=CC(OC)=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 18.27 50

Preparing Stock Solutions

The following data is based on the product molecular weight 365.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.74 mL 13.68 mL 27.37 mL
5 mM 0.55 mL 2.74 mL 5.47 mL
10 mM 0.27 mL 1.37 mL 2.74 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Shi et al (2011) Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139. ACS Med.Chem.Lett. 2 303


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Citations for TC-O 9311

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Literature in this Area

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GPCR

GPCR Product Listing

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