Talsupram hydrochloride

Discontinued Product

Talsupram hydrochloride (Cat. No. 4352) has been withdrawn from sale for commercial reasons.
Cat.No. 4352 - Talsupram hydrochloride | C20H25NS.HCl | CAS No. 25487-28-9
Description: Selective inhibitor of noradrenalin transporters
Chemical Name: 1,3-Dihydro-N,3,3-trimethyl-1-phenylbenzo[c]thiophene-1-propanamine hydrochloride
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity for Talsupram hydrochloride

Talsupram hydrochloride is a selective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC50 values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant.

Technical Data for Talsupram hydrochloride

M. Wt 347.95
Formula C20H25NS.HCl
Storage Desiccate at RT
Purity ≥98% (HPLC)
CAS Number 25487-28-9
PubChem ID 33013
Smiles CC2(C)SC(C3=CC=CC=C3)(CCCNC)C1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Talsupram hydrochloride

References for Talsupram hydrochloride

References are publications that support the biological activity of the product.

McConathy et al (2004) Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the NE transporter. Nucl.Med.Biol. 31 705 PMID: 15246361

Schou et al (2006) Synthesis and positron emission tomography evaluation of three NE transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol.Imaging Biol. 8 1

Rowlett et al (2004) Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors. J.Pharmacol.Exp.Ther. 310 342 PMID: 14985417

View Related Products by Product Action

View all Adrenergic Transporter Inhibitors

Keywords: Talsupram hydrochloride, Talsupram hydrochloride supplier, norepinephrine, reuptake, inhibitors, inhibits, noradrenaline, noradrenalin, transporters, NET, antidepressants, selective, Adrenergic, Transporters, 4352, Tocris Bioscience

Citations for Talsupram hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Talsupram hydrochloride.

Reviews for Talsupram hydrochloride

There are currently no reviews for this product. Be the first to review Talsupram hydrochloride and earn rewards!

Have you used Talsupram hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure