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Cat.No. 6427 - Tafluprost | C25H34F2O5 | CAS No. 209860-87-7
Description: Very high affinity FP receptor agonist
Chemical Name: 1-Methylethyl (5-Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate
Purity: ≥95% (HPLC)
Literature (6)

Biological Activity for Tafluprost

Tafluprost is a very high affinity FP receptor agonist (Ki = 0.4 nM). Reduces intraocular pressure (IOP) in animal models of ocular hypertension and normal animals.

Technical Data for Tafluprost

M. Wt 452.53
Formula C25H34F2O5
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 209860-87-7
PubChem ID 9868491
Smiles O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/C(F)(F)COC2=CC=CC=C2)[C@H](O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Tafluprost

Solubility Soluble in methyl acetate (supplied pre-dissolved -10mg/ml)

References for Tafluprost

References are publications that support the biological activity of the product.

Takagi et al (2004) Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug. Exp.Eye Res. 78 767 PMID: 15037111

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Keywords: Tafluprost, Tafluprost supplier, AFP-168, AFP168, ocular, hypertension, very, high, afifinity, FP, agonists, agonism, prostaglandins, IOP, Prostanoid, Receptors, 6427, Tocris Bioscience

Citations for Tafluprost

Citations are publications that use Tocris products.

Currently there are no citations for Tafluprost. Do you know of a great paper that uses Tafluprost from Tocris? Please let us know.

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