Tafluprost

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Cat.No. 6427 - Tafluprost | C25H34F2O5 | CAS No. 209860-87-7
Description: Very high affinity FP receptor agonist
Chemical Name: 1-Methylethyl (5-Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (6)

Biological Activity

Very high affinity FP receptor agonist (Ki = 0.4 nM). Reduces intraocular pressure (IOP) in animal models of ocular hypertension and normal animals.

Technical Data

M. Wt 452.53
Formula C25H34F2O5
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 209860-87-7
PubChem ID 9868491
InChI Key WSNODXPBBALQOF-VEJSHDCNSA-N
Smiles O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/C(F)(F)COC2=CC=CC=C2)[C@H](O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble in methyl acetate (supplied pre-dissolved -10mg/ml)

References

References are publications that support the biological activity of the product.

Takagi et al (2004) Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug. Exp.Eye Res. 78 767 PMID: 15037111


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Citations for Tafluprost

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Literature in this Area

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