SUN 11602

Discontinued Product

SUN 11602 (Cat. No. 4826) has been withdrawn from sale for commercial reasons.
Description: Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
Chemical Name: 4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide
Purity: ≥98% (HPLC)
Literature (5)

Biological Activity for SUN 11602

SUN 11602 is a basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.

Technical Data for SUN 11602

M. Wt 451.61
Formula C26H37N5O2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 704869-38-5
PubChem ID 22245705
Smiles NC1=C(C)C(C)=C(NCC(N(C)C2CCN(CC3=CC=C(C(N)=O)C=C3)CC2)=O)C(C)=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for SUN 11602

Certificate of Analysis / Product Datasheet
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References for SUN 11602

References are publications that support the biological activity of the product.

Murayama et al (2013) SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. ACS Chem.Neurosci. 4 266 PMID: 23421678

Keywords: SUN 11602, SUN 11602 supplier, SUN11602, basic, fibroblast, growth, factor, bFGF, calcium, binding, protein, calbindin-D28k, Calb, FGFR, receptor, ERK1, ERK2, 4826, Tocris Bioscience

Citations for SUN 11602

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Currently there are no citations for SUN 11602.

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