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Discontinued ProductSulfisoxazole (Cat. No. 0731) has been withdrawn from sale for commercial reasons.
Biological Activity for Sulfisoxazole
Sulfisoxazole is a selective ETA endothelin receptor antagonist (IC50 values are 600 and 2200 nM for ETA and ETB receptors respectively).
Technical Data for Sulfisoxazole
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Sulfisoxazole
References are publications that support the biological activity of the product.
Chan et al (1994) Identification of a new class of ETA selective endothelin antagonists by pharmacophore directed screening. Biochem.Biophys.Res.Commun. 201 228 PMID: 8198578
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Keywords: Sulfisoxazole, Sulfisoxazole supplier, Endothelin, ETA, antagonists, Receptors, 0731, Tocris Bioscience
Citations for Sulfisoxazole
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Currently there are no citations for Sulfisoxazole.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.