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Submit ReviewSPL 334 is a S-Nitrosoglutathione reductase inhibitor. Prevents weight loss, and attenuates lung inflammation and fibrosis in a bleomycin injury model of interstitial lung disease in mice.
M. Wt | 433.5 |
Formula | C22H15N3O3S2 |
Storage | Store at +4°C |
Purity | ≥98% (HPLC) |
CAS Number | 688347-51-5 |
PubChem ID | 3651705 |
InChI Key | UWWSCLNCHCROLL-UHFFFAOYSA-N |
Smiles | OC(C1=CC=C(C=C1)CN2C(C3=C(N=C2SCC4=C(C#N)C=CC=C4)C=CS3)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Luzina et al (2015) Pharmacological in vivo inhibition of S-nitrosoglutathione reductase attenuates bleomycin-induced inflammation and fibrosis. J.Pharmacol.Exp.Ther. 355 13 PMID: 26209236
Keywords: SPL 334, SPL 334 supplier, SPL334, S-nitrosoglutathione, reductase, inhibitors, inhibits, interstitial, lung, disease, Other, Dehydrogenases, 5809, Tocris Bioscience
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