SNOB 1 reagent

Discontinued Product

Unfortunately SNOB 1 reagent (Cat. No. 3879) has been withdrawn from sale for commercial reasons.
Cat.No. 3879 - SNOB 1 reagent | C13H21N3O2S | CAS No. 92924-45-3
Chemical Name: (3S,4S,6R)-5-{2-Oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl}-N-(prop-2-en-1-yl)pentanamide
Purity: ≥98% (HPLC)

Biological Activity

S-nitrosylated binding (SNOB) reagents detect cysteine residues that have been S-nitrosylated by nitric oxide. SNOB 1 can be used as part of a single-step assay to label S-nitrosylated proteins with biotin for detection by Western blotting or proteomic analysis. Negative SNOB 1 control (Cat. No. 3880) available.

Licensing Information

Sold under an exclusive agreement from Glythera Ltd.

Technical Data

M. Wt 283.39
Formula C13H21N3O2S
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 92924-45-3
Smiles O=C(N2)N[C@@]1([H])[C@]2([H])CS[C@H]1CCCCC(NCC=C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 283.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.53 mL 17.64 mL 35.29 mL
5 mM 0.71 mL 3.53 mL 7.06 mL
10 mM 0.35 mL 1.76 mL 3.53 mL
50 mM 0.07 mL 0.35 mL 0.71 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet


References are publications that support the products' biological activity.

Wang et al (2011) The Moxarella catarrhalis nitric oxide reductase is essential for nitric oxide detoxification. J.Bacteriology 193 2804 PMID:


Citations for SNOB 1 reagent

Citations are publications that use Tocris products.

Currently there are no citations for SNOB 1 reagent.

Commented out for usability testing


TODO: Add Reviews

Literature in this Area

Pathways for SNOB 1 reagent


TODO: Add Protocols