Discontinued Product

SHIP 2a (Cat. No. 6101) has been withdrawn from sale for commercial reasons.
Description: Cystathione γ lyase (CSE) inhibitor
Chemical Name: (R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide
Purity: ≥98% (HPLC)

Biological Activity for SHIP 2a

SHIP 2a is a cystathione γ lyase (CSE) inhibitor (IC50 = 6.3 μM). Inhibits H2S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo.

Technical Data for SHIP 2a

M. Wt 184.22
Formula C7H8N2O2S
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 2165706-30-7
PubChem ID 124221753
Smiles O=C([C@@H]1CSC(N1)=O)NCC#C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for SHIP 2a

References are publications that support the biological activity of the product.

Corvino et al (2016) Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci.Rep. 6 34398 PMID: 27708394

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Citations for SHIP 2a

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Currently there are no citations for SHIP 2a.

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