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Cystathione γ lyase (CSE) inhibitor (IC50 = 6.3 μM). Inhibits H2S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 184.22. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.43 mL||27.14 mL||54.28 mL|
|5 mM||1.09 mL||5.43 mL||10.86 mL|
|10 mM||0.54 mL||2.71 mL||5.43 mL|
|50 mM||0.11 mL||0.54 mL||1.09 mL|
References are publications that support the biological activity of the product.
Corvino et al (2016) Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci.Rep. 6 34398 PMID: 27708394
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Keywords: SHIP 2a, SHIP 2a supplier, SHIP2a, cystathionase, cystathione, gamma, lyase, CSE, γ, inhibitors, inhibits, hydrogen, sulphide, sulfide, H2S, Other, Lyases, 6101, Tocris Bioscience
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