You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for SAHM1
SAHM1 is a notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.
Technical Data for SAHM1
(Modifications: Ala-1 = N-terminal Ac & β-Ala, X = (S)-2-(4-pentenyl)alanine, X-9 and X-13 stapled together with a double bond)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SAHM1
|Solubility||Soluble to 1 mg/ml in water|
References for SAHM1
References are publications that support the biological activity of the product.
Ashley et al (2015) Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem 116 2598 PMID: 25914241
Bagheri et al (2018) Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields. J.Tissue Eng.Regen.Med. 12 304 PMID: 28482141
KleinJan et al (2018) The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J.Allergy Clin.Immunol. 142 76 PMID: 29111218
If you know of a relevant reference for SAHM1, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: SAHM1, SAHM1 supplier, Notch, pathway, inhibitors, inhibits, MAML1, complex, assembly, stapled, peptide, Other, Signaling, Stapled, Peptides, 6477, Tocris Bioscience
Citations for SAHM1
Citations are publications that use Tocris products.
Currently there are no citations for SAHM1. Do you know of a great paper that uses SAHM1 from Tocris? Please let us know.
Reviews for SAHM1
There are currently no reviews for this product. Be the first to review SAHM1 and earn rewards!
Have you used SAHM1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image