(S)-Methyl-L-thiocitrulline dihydrochloride

Discontinued Product

(S)-Methyl-L-thiocitrulline dihydrochloride (Cat. No. 0733) has been withdrawn from sale for commercial reasons.
Description: nNOS/iNOS inhibitor

Biological Activity

NO synthase inhibitor (IC50 values are 1.05 and 2.2 μM for rat nNOS and iNOS respectively). Has strong pressor activity in vivo.

Technical Data

M. Wt 278.2
Storage Desiccate at +4°C
CAS Number 156719-41-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service


References are publications that support the biological activity of the product.

Joly et al (1995) Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta. Br.J.Pharmacol. 115 491 PMID: 7582462

Narayanan et al (1995) S-alkyl-L-thiocitrullines. Potent stereoselective inhibitors of nitric oxide synthase with strong pressor activity in vivo. J.Biol.Chem. 270 11103 PMID: 7538112

Narayanan and Griffith (1994) Synthesis of L-thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline: a new class of potent nitric oxide synthase inhibitors. J.Med.Chem. 37 885 PMID: 7512141

View Related Products by Target

View Related Products by Product Action

View all Non-selective NOS Inhibitors

Keywords: (S)-Methyl-L-thiocitrulline dihydrochloride, (S)-Methyl-L-thiocitrulline dihydrochloride supplier, Non-selective, NOS, 0733, Tocris Bioscience

Citations for (S)-Methyl-L-thiocitrulline dihydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for (S)-Methyl-L-thiocitrulline dihydrochloride.

Reviews for (S)-Methyl-L-thiocitrulline dihydrochloride

There are currently no reviews for this product. Be the first to review (S)-Methyl-L-thiocitrulline dihydrochloride and earn rewards!

Have you used (S)-Methyl-L-thiocitrulline dihydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review