Pricing Availability Delivery Time Qty
Cat.No. 0455 - (S)-(-)-Carbidopa | C10H14N2O4 | CAS No. 28860-95-9
Description: Aromatic L-amino acid decarboxylase inhibitor
Chemical Name: (S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
Purity: ≥99% (HPLC)

Biological Activity

Peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

Technical Data

M. Wt 226.23
Formula C10H14N2O4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 28860-95-9
PubChem ID 34359
Smiles OC1=C(O)C=CC(C[C@@](NN)(C)C(O)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 4.52 20

Preparing Stock Solutions

The following data is based on the product molecular weight 226.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.42 mL 22.1 mL 44.2 mL
5 mM 0.88 mL 4.42 mL 8.84 mL
10 mM 0.44 mL 2.21 mL 4.42 mL
50 mM 0.09 mL 0.44 mL 0.88 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet


References are publications that support the products' biological activity.

Cheng et al (1992) Carbidopa inhibition of aromatic L-amino acid decarboxylase in rat brain capilliaries. FASEB J. 6 A1589 PMID:

Kopfhammer et al (1985) L-Dopa infusion experiments in combination with the L-dopa decarboxylase inhibitors benserazide and carbidopa - L-dopa metabolism and neuroendocrinological effects. Pharmacopsychiatry 18 143 PMID:

Merck Index 12 1843 PMID:

If you know of a relevant reference for (S)-(-)-Carbidopa, please let us know.

View Related Products by Product Action

View all Decarboxylase Inhibitors

Keywords: (S)-(-)-Carbidopa, supplier, Aromatic, Lamino, acid, decarboxylase, inhibitors, inhibits, Decarboxylases, Dopaminergic-Related, Decarboxylases, Tocris Bioscience

Citations for (S)-(-)-Carbidopa

Citations are publications that use Tocris products.

Currently there are no citations for (S)-(-)-Carbidopa. Do you know of a great paper that uses (S)-(-)-Carbidopa from Tocris? If so please let us know.

Reviews for (S)-(-)-Carbidopa

There are currently no reviews for this product. Be the first to review (S)-(-)-Carbidopa and earn rewards!

Have you used (S)-(-)-Carbidopa?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area


Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease