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Biological Activity for (S)-C33
(S)-C33 is a potent PDE9 inhibitor (IC50 = 11 nM).
Technical Data for (S)-C33
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (S)-C33
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for (S)-C33
The following data is based on the product molecular weight 357.84. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.79 mL||13.97 mL||27.95 mL|
|5 mM||0.56 mL||2.79 mL||5.59 mL|
|10 mM||0.28 mL||1.4 mL||2.79 mL|
|50 mM||0.06 mL||0.28 mL||0.56 mL|
References for (S)-C33
References are publications that support the biological activity of the product.
Huang et al (2015) Structural asymmetry of phosphodiesterase-9A and a unique pocket for selective binding of a potent enantiomeric inhibitor. Mol.Pharmacol. 88 836 PMID: 26316540
If you know of a relevant reference for (S)-C33, please let us know.
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Keywords: (S)-C33, (S)-C33 supplier, phosphodiesterase, PDE9, inhibitor, Potent, SC33, Phosphodiesterases, 6035, Tocris Bioscience
Citations for (S)-C33
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Literature in this Area
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