Discontinued Product

(S)-C33 (Cat. No. 6035) has been withdrawn from sale for commercial reasons.
Description: Potent PDE9 inhibitor
Chemical Name: 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity for (S)-C33

(S)-C33 is a potent PDE9 inhibitor (IC50 = 11 nM).

Technical Data for (S)-C33

M. Wt 357.84
Formula C18H20ClN5O
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 2066488-39-7
PubChem ID 91885385
Smiles C[C@@H](C1=CC=C(C=C1)Cl)NC2=NC(C3=C(N(C4CCCC4)N=C3)N2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for (S)-C33

References are publications that support the biological activity of the product.

Huang et al (2015) Structural asymmetry of phosphodiesterase-9A and a unique pocket for selective binding of a potent enantiomeric inhibitor. Mol.Pharmacol. 88 836 PMID: 26316540

View Related Products by Target

View Related Products by Product Action

View all Phosphodiesterase Inhibitors

Keywords: (S)-C33, (S)-C33 supplier, phosphodiesterase, PDE9, inhibitor, Potent, SC33, Phosphodiesterases, 6035, Tocris Bioscience

Citations for (S)-C33

Citations are publications that use Tocris products.

Currently there are no citations for (S)-C33.

Reviews for (S)-C33

There are currently no reviews for this product. Be the first to review (S)-C33 and earn rewards!

Have you used (S)-C33?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure