RS 56812 hydrochloride
A highly potent and selective 5-HT3 partial agonist, with a pKi at 5-HT3 receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors.
Sold with the permission of Roche Bioscience
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|phosphate buffered saline||34.78||100|
Preparing Stock Solutions
The following data is based on the product molecular weight 347.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.87 mL||14.37 mL||28.75 mL|
|5 mM||0.57 mL||2.87 mL||5.75 mL|
|10 mM||0.29 mL||1.44 mL||2.87 mL|
|50 mM||0.06 mL||0.29 mL||0.57 mL|
References are publications that support the products' biological activity.
If you know of a relevant reference for RS 56812 hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: RS 56812 hydrochloride, supplier, 5-HT3, partial, agonists, Serotonin, Receptors, RS56812, hydrochloride, 5-HT3, Receptors, 5-HT3, Receptors, Tocris Bioscience
1 Citation for RS 56812 hydrochloride
Citations are publications that use Tocris products. Selected citations for RS 56812 hydrochloride include:
Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Mol Psychiatry 7 2336 PMID: 26114334
Do you know of a great paper that uses RS 56812 hydrochloride from Tocris? If so please let us know.
Reviews for RS 56812 hydrochloride
There are currently no reviews for this product. Be the first to review RS 56812 hydrochloride and earn rewards!
Have you used RS 56812 hydrochloride?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.