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RLLFT-NH2 is a reversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.
Active Analog also available.
(Modifications: Thr-5 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 2 mg/ml in water|
References are publications that support the biological activity of the product.
Asfaha et al (2002) Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br.J.Pharmacol. 135 1101 PMID: 11877315
Fang et al (2003) Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J.Physiol. 549 903 PMID: 12717003
Buresi et al (2004) Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G337 PMID: 15345469
If you know of a relevant reference for RLLFT-NH2, please let us know.
Keywords: RLLFT-NH2, RLLFT-NH2 supplier, Control, peptide, TFLLR-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3393, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for RLLFT-NH2 include:
Chen et al (2012) Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 32 7622 PMID: 22649241
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