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Submit ReviewBiological Activity for RLLFT-NH2
RLLFT-NH2 is a reversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.
Active Analog also available.
Technical Data for RLLFT-NH2
| M. Wt | 647.82 |
| Formula | C31H53N9O6 |
| Sequence |
RLLFT (Modifications: Thr-5 = C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 447408-68-6 |
| PubChem ID | 56972203 |
| InChI Key | ILPOBMZRIPLMBB-GFGQVAFXSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for RLLFT-NH2
References for RLLFT-NH2
References are publications that support the biological activity of the product.
Asfaha et al (2002) Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br.J.Pharmacol. 135 1101 PMID: 11877315
Fang et al (2003) Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J.Physiol. 549 903 PMID: 12717003
Buresi et al (2004) Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G337 PMID: 15345469
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Keywords: RLLFT-NH2, RLLFT-NH2 supplier, Control, peptide, TFLLR-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3393, Tocris Bioscience
1 Citation for RLLFT-NH2
Citations are publications that use Tocris products. Selected citations for RLLFT-NH2 include:
Chen et al (2012) Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 32 7622 PMID: 22649241
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