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Description: Control peptide for TFLLR-NH2 (Cat. No. 1464)
Citations (1)

Biological Activity for RLLFT-NH2

RLLFT-NH2 is a reversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.

Active Analog also available.

Technical Data for RLLFT-NH2

M. Wt 647.82
Formula C31H53N9O6
Sequence RLLFT

(Modifications: Thr-5 = C-terminal amide)

Storage Store at -20°C
CAS Number 447408-68-6
PubChem ID 56972203
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for RLLFT-NH2

Solubility Soluble to 2 mg/ml in water

Product Datasheets for RLLFT-NH2

Certificate of Analysis / Product Datasheet
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References for RLLFT-NH2

References are publications that support the biological activity of the product.

Asfaha et al (2002) Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br.J.Pharmacol. 135 1101 PMID: 11877315

Fang et al (2003) Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J.Physiol. 549 903 PMID: 12717003

Buresi et al (2004) Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G337 PMID: 15345469

If you know of a relevant reference for RLLFT-NH2, please let us know.

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Keywords: RLLFT-NH2, RLLFT-NH2 supplier, Control, peptide, TFLLR-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3393, Tocris Bioscience

1 Citation for RLLFT-NH2

Citations are publications that use Tocris products. Selected citations for RLLFT-NH2 include:

Chen et al (2012) Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 32 7622 PMID: 22649241

Do you know of a great paper that uses RLLFT-NH2 from Tocris? Please let us know.

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