Amidst rising costs across all areas of our business, and aggressive attempts to implement cost savings without sacrificing quality, we announce the need to implement a cost increase starting July 1, 2022. If you have questions, please contact your sales representative.
The Receptor Interacting Protein (RIP) kinase family comprises seven threonine/serine and tyrosine kinases (RIP1 - 7), that are involved in various biological processes, including innate immunity, inflammation and regulation of cell death. They are characterized by a homologous kinase domain, but have distinct non-kinase regions, which are key to the specific function of each RIP kinase. RIP1-5 all have a N-terminal kinase domain, while RIP6 and RIP7 (also known as LRRK1 and LRRK2, respectively) contain multiple and diverse domain structures, including a leucine-rich repeat region, in addition to the kinase domain.