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Gene switch ligand. Transcription inducer for use in inducible gene expression systems. Does not cause significant changes in endogenous gene expression in HEK cells.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 382.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.61 mL||13.07 mL||26.14 mL|
|5 mM||0.52 mL||2.61 mL||5.23 mL|
|10 mM||0.26 mL||1.31 mL||2.61 mL|
|50 mM||0.05 mL||0.26 mL||0.52 mL|
References are publications that support the biological activity of the product.
Panguluri et al (2007) Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells. FEBS Journal 274 5669 PMID: 17922837
Lapenna et al (2009) Semi-synthetic ecdysteroids as gene-switch actuators: synthesis, structure-activity relationships, and prospective ADME properties. ChemMedChem 4 55 PMID: 19065574
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