RG 102240

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Cat.No. 5761 - RG 102240 | C23H30N2O3 | CAS No. 162326-49-0
Description: Gene switch ligand for use in inducible gene expression systems
Alternative Names: RSL1
Chemical Name: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
Purity: ≥98% (HPLC)

Biological Activity for RG 102240

RG 102240 is a gene switch ligand. Transcription inducer for use in inducible gene expression systems. Does not cause significant changes in endogenous gene expression in HEK cells.

Technical Data for RG 102240

M. Wt 382.5
Formula C23H30N2O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 162326-49-0
PubChem ID 9929888
Smiles O=C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)C1=CC=CC(OC)=C1CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for RG 102240

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 38.25 100
ethanol 38.25 100

Preparing Stock Solutions for RG 102240

The following data is based on the product molecular weight 382.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.61 mL 13.07 mL 26.14 mL
5 mM 0.52 mL 2.61 mL 5.23 mL
10 mM 0.26 mL 1.31 mL 2.61 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

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References for RG 102240

References are publications that support the biological activity of the product.

Panguluri et al (2007) Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells. FEBS Journal 274 5669 PMID: 17922837

Lapenna et al (2009) Semi-synthetic ecdysteroids as gene-switch actuators: synthesis, structure-activity relationships, and prospective ADME properties. ChemMedChem 4 55 PMID: 19065574

If you know of a relevant reference for RG 102240, please let us know.

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Citations for RG 102240

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