RG 102240

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Cat.No. 5761 - RG 102240 | C23H30N2O3 | CAS No. 162326-49-0
Description: Gene switch ligand for use in inducible gene expression systems
Alternative Names: RSL1
Chemical Name: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Gene switch ligand. Transcription inducer for use in inducible gene expression systems. Does not cause significant changes in endogenous gene expression in HEK cells.

Technical Data

M. Wt 382.5
Formula C23H30N2O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 162326-49-0
PubChem ID 9929888
InChI Key QYYXITIZXRMPSZ-UHFFFAOYSA-N
Smiles O=C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)C1=CC=CC(OC)=C1CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 38.25 100
ethanol 38.25 100

Preparing Stock Solutions

The following data is based on the product molecular weight 382.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.61 mL 13.07 mL 26.14 mL
5 mM 0.52 mL 2.61 mL 5.23 mL
10 mM 0.26 mL 1.31 mL 2.61 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Panguluri et al (2007) Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells. FEBS Journal 274 5669 PMID: 17922837

Lapenna et al (2009) Semi-synthetic ecdysteroids as gene-switch actuators: synthesis, structure-activity relationships, and prospective ADME properties. ChemMedChem 4 55 PMID: 19065574


If you know of a relevant reference for RG 102240, please let us know.

Keywords: RG 102240, supplier, RG102240, RheoSwitch, Ligands, inducible, expression, sytems, gene, switch, transcription, ecdysone, receptors, EcR, RSL1, Other, Transcription, Factors, DNA,, RNA, and, Protein, Synthesis, Other, Transcription, Factors, Tocris Bioscience

Citations for RG 102240

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