Ractopamine hydrochloride
Biological Activity
Trace amine 1 (TA1) receptor agonist; increases chloride conductance in oocytes coexpressing hCFTR and mouse TA1 receptors.
Technical Data
M. Wt | 337.84 |
Formula | C18H23NO3.HCl |
Storage | Desiccate at RT |
Purity | ≥97% (HPLC) |
CAS Number | 90274-24-1 |
PubChem ID | 14010333 |
InChI Key | JHGSLSLUFMZUMK-UHFFFAOYSA-N |
Smiles | OC1=CC=C(C(O)CNC(CCC2=CC=C(O)C=C2)C)C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
water | 6.76 | 20 | |
DMSO | 33.78 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 337.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.96 mL | 14.8 mL | 29.6 mL |
5 mM | 0.59 mL | 2.96 mL | 5.92 mL |
10 mM | 0.3 mL | 1.48 mL | 2.96 mL |
50 mM | 0.06 mL | 0.3 mL | 0.59 mL |
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References
References are publications that support the biological activity of the product.
Liu et al (2014) Ractopamine, a livestock feed additive, is a full agonist at trace amine-associated receptor 1. J.Pharmacol.Exp.Ther. 350 124 PMID: 24799633
If you know of a relevant reference for Ractopamine hydrochloride, please let us know.
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Keywords: Ractopamine hydrochloride, Ractopamine hydrochloride supplier, Trace, amine, 1, TA1, receptors, agonists, agonism, chloride, conductance, TAAR, Amine, Receptor, 5252, Tocris Bioscience
Citations for Ractopamine hydrochloride
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.
Schizophrenia Poster
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.