Quinolinic acid

Discontinued Product

Quinolinic acid (Cat. No. 0225) has been withdrawn from sale for commercial reasons.
Description: Endogenous NMDA agonist and transmitter candidate
Chemical Name: Pyridine-2,3-dicarboxylic acid
Citations (1)
Literature (5)

Biological Activity for Quinolinic acid

Quinolinic acid is an endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.

Technical Data for Quinolinic acid

M. Wt 167.12
Formula C7H5NO4
Storage Store at RT
CAS Number 89-00-9
PubChem ID 1066
Smiles OC(=O)C1=C(N=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Quinolinic acid

Certificate of Analysis / Product Datasheet
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References for Quinolinic acid

References are publications that support the biological activity of the product.

Monaghan and Beaton (1991) Quinolinate differentiates between forebrain and cerebellar NMDA receptors. Eur.J.Pharmacol. 194 123 PMID: 1676371

Prada de Carvalho et al (1996) The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem.Int. 28 445 PMID: 8740453

Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Prog.Neurobiol. 30 333 PMID: 2830636

Stone and Perkins (1981) Quinolinic acid: a potent endogenous excitant at amino acid receptors in the rat CNS. Eur.J.Pharmacol. 72 411 PMID: 6268428

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Keywords: Quinolinic acid, Quinolinic acid supplier, agonists, Transmitter, candidate, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0225, Tocris Bioscience

1 Citation for Quinolinic acid

Citations are publications that use Tocris products. Selected citations for Quinolinic acid include:

Tsutsui-Kimura et al (2015) Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex. Nat Commun 18 PMID: 25522418

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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