Dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.
Sold with the permission of Eli Lilly and Company
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 319.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.13 mL||15.66 mL||31.32 mL|
|5 mM||0.63 mL||3.13 mL||6.26 mL|
|10 mM||0.31 mL||1.57 mL||3.13 mL|
|50 mM||0.06 mL||0.31 mL||0.63 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Foreman et al (1989) Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist. J.Pharmacol.Exp.Ther. 250 227 PMID: 2526214
Eaton et al (1994) Effects of the selective dopaminergic D2 agonist quinelorane on the activity of dopaminergic and noradrenergic neurons projecting to the diencephalon of the rat. J.Pharmacol.Exp.Ther. 268 645 PMID: 7906734
Flietstra and Levant (1998) Comparison of D2 and D3 dopamine receptor affinity of dopaminergic compounds in the rat brain. Life Sci. 62 1825 PMID: 9600324
If you know of a relevant reference for Quinelorane hydrochloride, please let us know.
View Related Products by Product Action
Keywords: Quinelorane hydrochloride, supplier, D2, D3, agonists, Dopamine, D2-like, Non-Selective, Receptors, dopaminergic, LY163502, LY, 163502, Non-selective, Dopamine, Tocris Bioscience
Citations for Quinelorane hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Quinelorane hydrochloride. Do you know of a great paper that uses Quinelorane hydrochloride from Tocris? If so please let us know.
Literature in this Area
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.