Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 445.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.24 mL||11.22 mL||22.45 mL|
|5 mM||0.45 mL||2.24 mL||4.49 mL|
|10 mM||0.22 mL||1.12 mL||2.24 mL|
|50 mM||0.04 mL||0.22 mL||0.45 mL|
References are publications that support the biological activity of the product.
Zhou et al (2007) Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1. Mol.Pharmacol. 72 976 PMID: 17652444
Corminboeuf et al (2014) FPR2/ALXR agonists and the resolution of inflammation. J.Med.Chem. 58 537 PMID: 25365541
If you know of a relevant reference for Quin C1, please let us know.
View Related Products by Product Action
Keywords: Quin C1, Quin C1 supplier, QuinC1, potent, selective, agonists, agonism, FPR2, FPRL1, formyl, peptide, receptor-like, 1, inflammation, anti-inflammatory, Formyl, Peptide, Receptors, 5583, Tocris Bioscience
1 Citation for Quin C1
Citations are publications that use Tocris products. Selected citations for Quin C1 include:
Ma et al (2015) Agonist and antagonist effects of aripiprazole on D2-like receptors controlling rat brain DA synthesis depend on the DArgic tone. Int J Neuropsychopharmacol 18 PMID: 25522390
Do you know of a great paper that uses Quin C1 from Tocris? Please let us know.
Reviews for Quin C1
There are currently no reviews for this product. Be the first to review Quin C1 and earn rewards!
Have you used Quin C1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.