Reversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 455.45. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.39 mL||21.96 mL||43.91 mL|
|2.5 mM||0.88 mL||4.39 mL||8.78 mL|
|5 mM||0.44 mL||2.2 mL||4.39 mL|
|25 mM||0.09 mL||0.44 mL||0.88 mL|
References are publications that support the biological activity of the product.
Alexander et al (2011) Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc.Natl.Acad.Sci.USA 108 15828 PMID: 21896756
If you know of a relevant reference for Qc 1, please let us know.
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Keywords: Qc 1, Qc 1 supplier, Qc1, threonine, dehydrogenase, inhibitors, inhibits, TDH, Other, Dehydrogenases, 5055, Tocris Bioscience
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