Pronethalol hydrochloride

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Cat.No. 0829 - Pronethalol hydrochloride | C15H19NO.HCl | CAS No. 51-02-5
Description: β antagonist
Alternative Names: ICI-38174
Chemical Name: 2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride
Purity: ≥99% (HPLC)
Citations (1)
Literature (4)

Biological Activity for Pronethalol hydrochloride

Pronethalol hydrochloride is an β-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data for Pronethalol hydrochloride

M. Wt 265.78
Formula C15H19NO.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 51-02-5
PubChem ID 60975
Smiles Cl.CC(C)NCC(O)C1=CC=C2C=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Pronethalol hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
water 100

Preparing Stock Solutions for Pronethalol hydrochloride

The following data is based on the product molecular weight 265.78. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.76 mL 18.81 mL 37.63 mL
5 mM 0.75 mL 3.76 mL 7.53 mL
10 mM 0.38 mL 1.88 mL 3.76 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

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Product Datasheets for Pronethalol hydrochloride

References for Pronethalol hydrochloride

References are publications that support the biological activity of the product.

Main (1990) α-Adrenergic receptors. Comprehensive Medicinal Chemistry. Ed Hansch 3 187

Merck Index 12 7974

If you know of a relevant reference for Pronethalol hydrochloride, please let us know.

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View all Non-selective Adrenergic β Receptor Antagonists

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1 Citation for Pronethalol hydrochloride

Citations are publications that use Tocris products. Selected citations for Pronethalol hydrochloride include:

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther 329 350 PMID: 19144685

Do you know of a great paper that uses Pronethalol hydrochloride from Tocris? Please let us know.

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Literature in this Area

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