Pronethalol hydrochloride

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Cat.No. 0829 - Pronethalol hydrochloride | C15H19NO.HCl | CAS No. 51-02-5
Description: β antagonist
Alternative Names: ICI-38174
Chemical Name: 2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

β-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt 265.78
Formula C15H19NO.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 51-02-5
PubChem ID 60975
InChI Key QONLGXRPRAIDGI-UHFFFAOYSA-N
Smiles Cl.CC(C)NCC(O)C1=CC=C2C=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 265.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.76 mL 18.81 mL 37.63 mL
5 mM 0.75 mL 3.76 mL 7.53 mL
10 mM 0.38 mL 1.88 mL 3.76 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Main (1990) α-Adrenergic receptors. Comprehensive Medicinal Chemistry. Ed Hansch 3 187 PMID:

Merck Index 12 7974 PMID:


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View Related Products by Product Action

View all Non-selective Adrenergic β Receptor Antagonists

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1 Citation for Pronethalol hydrochloride

Citations are publications that use Tocris products. Selected citations for Pronethalol hydrochloride include:

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther 329 350 PMID: 19144685


Do you know of a great paper that uses Pronethalol hydrochloride from Tocris? If so please let us know.

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