PMX 53c

Pricing Availability Delivery Time Qty
Cat.No. 5697 - PMX 53c | Ac-Phe-cyclo(Orn-Pro-D-Cha-Ala-D-Arg)
Description: Negative control for PMX 53 (Cat. No. 5473)
Datasheet
Citations
Literature

Biological Activity

Negative control for PMX 53 (Cat. No. 5473).

Technical Data

M. Wt 780.96
Formula C39H60N10O7
Sequence FXPXAR

(Modifications: Phe-1 = N-terminal Ac, X-2 = Orn, X-4 = D-Cha, Arg-6 = D-Arg, Lactam bridge: Orn-2 to Arg-6 )

Storage Store at -20°C
PubChem ID 121513884
InChI Key RCANPSOYHAFQSD-UHFFFAOYSA-N
Smiles CC1NC(=O)C(CC2CCCCC2)NC(=O)C2CCCN2C(=O)C(CCCNC(=O)C(CCCN=C(N)N)NC1=O)NC(=O)C(Cc1ccccc1)NC(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 780.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.28 mL 6.4 mL 12.8 mL
5 mM 0.26 mL 1.28 mL 2.56 mL
10 mM 0.13 mL 0.64 mL 1.28 mL
50 mM 0.03 mL 0.13 mL 0.26 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Subramanian et al (2011) PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Mol.Pharmacol. 79 1005 PMID: 21441599


If you know of a relevant reference for PMX 53c, please let us know.

View Related Products by Target

Keywords: PMX53c negative control PMX53 complement antagonists CD88 MrgX2 Complement

Citations for PMX 53c

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Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

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Immunology

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
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Pathways for PMX 53c

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