You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Photo-lenalidomide-acid is a functionalized cereblon ligand containing a dimethoxy azo-benzene photoswitch; for use as a precursor to photoswitchable Degraders (PHOTACs). Photo-lenalidomide-acid is supplied with a carboxylic acid functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for Degrader R&D.
This product is provided for use in onward chemistry. Suitable solvents can be used.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Reynders et al (2020) PHOTACs enable optical control of protein degradation. Sci.Adv. 6 eaay5064 PMID: 32128406
If you know of a relevant reference for Photo-lenalidomide-acid, please let us know.
Keywords: Photo-lenalidomide-acid, Photo-lenalidomide-acid supplier, PROTACs, degraders, building, blocks, photoswitchable, carboxylic, acid, functionalized, cereblon, e3, ligase, ligand, targeted, protein, degradation, tpd, Functionalized, E3, Ligase, Ligands, 7328, Tocris Bioscience
Citations for Photo-lenalidomide-acid
Citations are publications that use Tocris products.
Currently there are no citations for Photo-lenalidomide-acid. Do you know of a great paper that uses Photo-lenalidomide-acid from Tocris? Please let us know.
Reviews for Photo-lenalidomide-acid
There are currently no reviews for this product. Be the first to review Photo-lenalidomide-acid and earn rewards!
Have you used Photo-lenalidomide-acid?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Targeted Protein Degradation Poster
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia