PF 998425

Discontinued Product

PF 998425 (Cat. No. 3923) has been withdrawn from sale for commercial reasons.
Cat.No. 3923 - PF 998425 | C14H14F3NO | CAS No. 1076225-27-8
Description: Non-steroidal androgen receptor antagonist
Chemical Name: 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Selective non-steroidal androgen receptor (AR) antagonist (IC50 values are 26 nM and 90 nM in AR binding assays and cellular assays respectively). Displays low affinity for progesterone receptor (IC50 > 10 μM). Active in vivo.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M. Wt 269.26
Formula C14H14F3NO
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 1076225-27-8
PubChem ID 25093231
InChI Key MENRRRXHFQYXDW-DGCLKSJQSA-N
Smiles O[C@H](CCCC2)[C@H]2[C@]1=CC(C(F)(F)F)=C(C#N)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: PF 998425, PF 998425 supplier, selective, nonsteroidal, androgen, receptors, antagonists, PF998425, Pfizer, Androgen, Receptor, 3923, Tocris Bioscience

Citations for PF 998425

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