Peptide F9

Discontinued Product

Peptide F9 (Cat. No. 1903) has been withdrawn from sale for commercial reasons.
Cat.No. 1903 - Peptide F9 | Arg-Tyr-Val-Val-Leu-Pro-Arg-Pro-Val-Cys-Phe-Glu-Lys-Gly-Met-Asn-Tyr-Thr-Val-Arg | CAS No. 117609-40-2
Description: Inhibits laminin-mediated cell adhesion and migration
Datasheet
Citations
Reviews
Literature

Biological Activity

Peptide derived from the heparin-binding domain in the B1 chain of laminin. Binds to heparin, promotes cell adhesion, and inhibits the migration towards, and adhesion of metastatic fibrosarcoma cells to laminin.

Technical Data

M. Wt 2427.9
Formula C110H175N31O27S2
Sequence RYVVLPRPVCFEKGMNYTVR
Storage Desiccate at -20°C
CAS Number 117609-40-2
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Charonis et al (1988) A novel synthetic peptide from the B1 chanin of laminin with heparin-binding and cell adhesion-promoting activities. J.Cell Biol. 107 1253 PMID: 3417782

Schuger et al (1996) Laminin and heparan sulfate proteoglycan mediate epithelial cell polarization in organotypic cultures of embryonic lung cells: evidence implicating involvement of the inner globular region of laminin β 1 chain and the heparan sulfate groups of hepara Dev.Biol. 179 264 PMID: 8873769

Skubitz et al (1990) Definition of a sequence, RYVVLPR, within laminin peptide F-9 that mediates metastatic fibrosarcoma cell adhesion and spreading. Cancer Res. 50 7612 PMID: 2253210

Keywords: Peptide F9, Peptide F9 supplier, inhibitors, inhibits, laminin-mediated, cell, adhesion, migration, Adhesion, Molecules, heparin, PeptideF9, Cell, 1903, Tocris Bioscience

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