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Submit ReviewPEN (rat)
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Biological Activity
Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Technical Data
| M. Wt | 2301.62 |
| Formula | C102H169N27O33 |
| Sequence | AVDQDLGPEVPPENVLGALLRV |
| Storage | Store at -20°C |
| CAS Number | 569364-13-2 |
| PubChem ID | 131648254 |
| InChI Key | YANQFMRESNNLQN-CPPASMBOSA-N |
| Smiles | [H]N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solubility | Soluble to 1 mg/ml in PBS (pH 7.4) |
Product Datasheets
References
References are publications that support the biological activity of the product.
Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal. 9 ra43 PMID: 27117253
Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem.Neurosci. 10 1884 PMID: 30726666
If you know of a relevant reference for PEN (rat), please let us know.
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Keywords: PEN (rat), PEN (rat) supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), 6309, Tocris Bioscience
Citations for PEN (rat)
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