PEN (human)

Pricing Availability   Qty
Cat.No. 6307 - PEN (human) | Ala-Ala-Asp-His-Asp-Val-Gly-Ser-Glu-Leu-Pro-Pro-Glu-Gly-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val | CAS No. 597578-70-6
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.

Technical Data

M. Wt 2215.49
Formula C97H159N27O32
Sequence AADHDVGSELPPEGVLGALLRV
Storage Store at -20°C
CAS Number 597578-70-6
PubChem ID 16139549
InChI Key PEIJMGIGWZOADR-UCVVRVGMSA-N
Smiles [H]N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in PBS (pH 7.4)

References

References are publications that support the biological activity of the product.

Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal 9 ra43 PMID: 27117253


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Keywords: PEN (human), PEN (human) supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), 6307, Tocris Bioscience

Citations for PEN (human)

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Literature in this Area

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