PEN (human)

Pricing Availability Delivery Time Qty
Cat.No. 6307 - PEN (human) | Ala-Ala-Asp-His-Asp-Val-Gly-Ser-Glu-Leu-Pro-Pro-Glu-Gly-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val | CAS No. 597578-70-6
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Datasheet
Citations
Literature

Biological Activity

Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.

Technical Data

M. Wt 2215.49
Formula C97H159N27O32
Sequence AADHDVGSELPPEGVLGALLRV
Storage Store at -20°C
CAS Number 597578-70-6
PubChem ID 16139549
InChI Key PEIJMGIGWZOADR-UCVVRVGMSA-N
Smiles [H]N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in PBS (pH 7.4)

Preparing Stock Solutions

The following data is based on the product molecular weight 2215.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.45 mL 2.26 mL 4.51 mL
5 mM 0.09 mL 0.45 mL 0.9 mL
10 mM 0.05 mL 0.23 mL 0.45 mL
50 mM 0.01 mL 0.05 mL 0.09 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal 9 ra43 PMID: 27117253


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Keywords: PEN (human), supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), Orphan, 7-TM, Receptors, Orphan, 7-TM, Receptors, Tocris Bioscience

Citations for PEN (human)

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