PDD 00031705

Pricing Availability   Qty
Cat.No. 7009 - PDD 00031705 | C20H22N6O3S3 | CAS No. 2032096-45-8
Description: Negative control for PDD 00017238 (Cat. No. 7007)
Chemical Name: 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimidazole-5-sulfonamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Negative control for PDD 00017238 (Cat. No. 7007).

Technical Data

M. Wt 490.62
Formula C20H22N6O3S3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2032096-45-8
PubChem ID 123131658
InChI Key KWGUETFSHQZXMA-UHFFFAOYSA-N
Smiles CN(S(=O)(C1=CC=C2N(C(N(C2=C1)C3=NC=NS3)=O)CC4=C(N=C(S4)C)C)=O)C5(CC5)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 4.91 10

Preparing Stock Solutions

The following data is based on the product molecular weight 490.62. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.38 mL 101.91 mL 203.82 mL
0.5 mM 4.08 mL 20.38 mL 40.76 mL
1 mM 2.04 mL 10.19 mL 20.38 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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References

References are publications that support the biological activity of the product.

James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID: 27689388


If you know of a relevant reference for PDD 00031705, please let us know.

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Keywords: PDD 00031705, PDD 00031705 supplier, PDD00031705, poly, ADP, ribose, glycohydrolase, PARG, inhibitors, negative, controls, Poly(ADP)-ribose, Glycohydrolase, 7009, Tocris Bioscience

Citations for PDD 00031705

Citations are publications that use Tocris products.

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Literature in this Area

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Cancer

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