Discontinued ProductUnfortunately [Orn8]-Urotensin II (Cat. No. 1619) has been withdrawn from sale for commercial reasons.
Partial agonist peptide for the urotensin-II (UT) receptor. Acts as a full agonist at recombinant rat and human UT receptors (pEC50 ~ 8) but behaves as a competitive antagonist (pA2 = 6.56) in rat aorta.
(Modifications: X = Orn, Disulfide bridge between 5 - 10)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 1374.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.73 mL||3.64 mL||7.28 mL|
|5 mM||0.15 mL||0.73 mL||1.46 mL|
|10 mM||0.07 mL||0.36 mL||0.73 mL|
|50 mM||0.01 mL||0.07 mL||0.15 mL|
References are publications that support the products' biological activity.
Camarda et al (2002) A new ligand for the urotensin II receptor. Br.J.Pharmacol. 137 311 PMID: 12237249
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