[Orn8]-Urotensin II

Discontinued Product

[Orn8]-Urotensin II (Cat. No. 1619) has been withdrawn from sale for commercial reasons.
Description: Urotensin-II (UT) receptor partial agonist
Datasheet
Citations
Reviews
Literature (4)

Biological Activity for [Orn8]-Urotensin II

Partial agonist peptide for the urotensin-II (UT) receptor. Acts as a full agonist at recombinant rat and human UT receptors (pEC50 ~ 8) but behaves as a competitive antagonist (pA2 = 6.56) in rat aorta.

Technical Data for [Orn8]-Urotensin II

M. Wt 1374.54
Formula C63H83N13O18S2
Sequence ETPDCFWXYCV

(Modifications: X = Orn, Disulfide bridge between 5 - 10)

Storage Desiccate at -20°C
CAS Number 479065-85-5
Smiles [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for [Orn8]-Urotensin II

References for [Orn8]-Urotensin II

References are publications that support the biological activity of the product.

Camarda et al (2002) A new ligand for the urotensin II receptor. Br.J.Pharmacol. 137 311 PMID: 12237249

View Related Products by Product Action

View all Urotensin-II Receptor Agonists

Keywords: [Orn8]-Urotensin II, [Orn8]-Urotensin II supplier, Urotensin-II, UT, receptor, partial, agonists, Receptors, [Orn8]-UrotensinII, 1619, Tocris Bioscience

Citations for [Orn8]-Urotensin II

Citations are publications that use Tocris products.

Currently there are no citations for [Orn8]-Urotensin II.

Reviews for [Orn8]-Urotensin II

There are currently no reviews for this product. Be the first to review [Orn8]-Urotensin II and earn rewards!

Have you used [Orn8]-Urotensin II?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure
GPCR Product Listing

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
Cardiovascular Poster

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.