[Orn8]-Urotensin II

Discontinued Product

[Orn8]-Urotensin II (Cat. No. 1619) has been withdrawn from sale for commercial reasons.
Description: Urotensin-II (UT) receptor partial agonist
Datasheet
Citations
Reviews

Biological Activity for [Orn8]-Urotensin II

Partial agonist peptide for the urotensin-II (UT) receptor. Acts as a full agonist at recombinant rat and human UT receptors (pEC50 ~ 8) but behaves as a competitive antagonist (pA2 = 6.56) in rat aorta.

Technical Data for [Orn8]-Urotensin II

M. Wt 1374.54
Formula C63H83N13O18S2
Sequence ETPDCFWXYCV

(Modifications: X = Orn, Disulfide bridge between 5 - 10)

Storage Desiccate at -20°C
CAS Number 479065-85-5
Smiles [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for [Orn8]-Urotensin II

References for [Orn8]-Urotensin II

References are publications that support the biological activity of the product.

Camarda et al (2002) A new ligand for the urotensin II receptor. Br.J.Pharmacol. 137 311 PMID: 12237249

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Keywords: [Orn8]-Urotensin II, [Orn8]-Urotensin II supplier, Urotensin-II, UT, receptor, partial, agonists, Receptors, [Orn8]-UrotensinII, 1619, Tocris Bioscience

Citations for [Orn8]-Urotensin II

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Currently there are no citations for [Orn8]-Urotensin II.

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