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Description: Urotensin-II (UT) receptor partial agonist
Biological Activity for [Orn8]-Urotensin II
Partial agonist peptide for the urotensin-II (UT) receptor. Acts as a full agonist at recombinant rat and human UT receptors (pEC50 ~ 8) but behaves as a competitive antagonist (pA2 = 6.56) in rat aorta.
Technical Data for [Orn8]-Urotensin II
| M. Wt | 1374.54 |
| Formula | C63H83N13O18S2 |
| Sequence |
ETPDCFWXYCV (Modifications: X = Orn, Disulfide bridge between 5 - 10) |
| Storage | Desiccate at -20°C |
| CAS Number | 479065-85-5 |
| Smiles | [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for [Orn8]-Urotensin II
References for [Orn8]-Urotensin II
References are publications that support the biological activity of the product.
Camarda et al (2002) A new ligand for the urotensin II receptor. Br.J.Pharmacol. 137 311 PMID: 12237249
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Keywords: [Orn8]-Urotensin II, [Orn8]-Urotensin II supplier, Urotensin-II, UT, receptor, partial, agonists, Receptors, [Orn8]-UrotensinII, 1619, Tocris Bioscience
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