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Partial agonist peptide for the urotensin-II (UT) receptor. Acts as a full agonist at recombinant rat and human UT receptors (pEC50 ~ 8) but behaves as a competitive antagonist (pA2 = 6.56) in rat aorta.
(Modifications: X = Orn, Disulfide bridge between 5 - 10)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Camarda et al (2002) A new ligand for the urotensin II receptor. Br.J.Pharmacol. 137 311 PMID: 12237249
Keywords: [Orn8]-Urotensin II, [Orn8]-Urotensin II supplier, Urotensin-II, UT, receptor, partial, agonists, Receptors, [Orn8]-UrotensinII, 1619, Tocris Bioscience
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