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Oligomycin A is an inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 791.06. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||12.64 mL||63.21 mL||126.41 mL|
|0.5 mM||2.53 mL||12.64 mL||25.28 mL|
|1 mM||1.26 mL||6.32 mL||12.64 mL|
|5 mM||0.25 mL||1.26 mL||2.53 mL|
References are publications that support the biological activity of the product.
Salomon et al (2001) Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem.Biol. 8 71 PMID: 11182320
If you know of a relevant reference for Oligomycin A, please let us know.
Keywords: Oligomycin A, Oligomycin A supplier, OligomycinA, inhibitors, mitochondrial, ATPase, inhibits, oxidative, phosphorylation, antibiotics, Other, ATPases, Antibiotics, 4110, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Oligomycin A include:
Shin et al (2017) Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice. Cell Metab 26 764 PMID: 28988822
Depaoli et al (2018) Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells. Cell Rep 25 501 PMID: 30304688
Banh et al (2016) PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia. Nat Cell Biol 18 803 PMID: 27323329
Do you know of a great paper that uses Oligomycin A from Tocris? Please let us know.
Average Rating: 4 (Based on 1 Review.)
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