Ogerin

Pricing Availability   Qty
Cat.No. 5722 - Ogerin | C17H17N5O | CAS No. 1309198-71-7
Description: Selective positive allosteric modulator at GPR68
Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Selective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.

Technical Data

M. Wt 307.35
Formula C17H17N5O
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1309198-71-7
PubChem ID 56707820
InChI Key MDGIEDNDSFMSLP-UHFFFAOYSA-N
Smiles NC1=NC(NCC2=CC=CC=C2)=NC(C3=CC=CC=C3CO)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 6.15 20
DMSO 30.73 100

Preparing Stock Solutions

The following data is based on the product molecular weight 307.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.25 mL 16.27 mL 32.54 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
10 mM 0.33 mL 1.63 mL 3.25 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Huang et al (2015) Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature 527 477 PMID: 26550826


If you know of a relevant reference for Ogerin, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Orphan 7-TM Receptor Modulators

Keywords: Ogerin, Ogerin supplier, positive, allosteric, modulators, GPR68, selective, learning, memory, Orphan, 7-TM, Receptors, 5722, Tocris Bioscience

Citations for Ogerin

Citations are publications that use Tocris products.

Currently there are no citations for Ogerin. Do you know of a great paper that uses Ogerin from Tocris? Please let us know.

Reviews for Ogerin

There are currently no reviews for this product. Be the first to review Ogerin and earn rewards!

Have you used Ogerin?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling