Obestatin (rat)

Pricing Availability Delivery Time Qty
Cat.No. 2445 - Obestatin (rat) | Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2 | CAS No. 869705-22-6
Description: Endogenous reported anorexigenic peptide
Datasheet
Citations
Literature

Biological Activity

Endogenous peptide derived from the same prepropeptide as ghrelin. Reported to suppress food intake and reduce body weight-gain in rats.

Technical Data

M. Wt 2516.84
Formula C114H174N34O31
Sequence FNAPFDVGIKLSGAQYQQHGRAL

(Modifications: Leu-23 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 869705-22-6
PubChem ID 16186202
InChI Key OJSXICLEROKMBP-FFUDWAICSA-N
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2516.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.4 mL 1.99 mL 3.97 mL
5 mM 0.08 mL 0.4 mL 0.79 mL
10 mM 0.04 mL 0.2 mL 0.4 mL
50 mM 0.01 mL 0.04 mL 0.08 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Zhang et al (2005) Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310 996 PMID: 16284174

Nogueiras and Tschop (2005) Biomedicine. Separation of conjoined hormones yields appetite rivals. Science 310 985 PMID: 16284170

Pan and Kastin (2006) Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides 27 911 PMID: 16476508


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Keywords: Obestatin (rat), supplier, Endogenous, anorexigenic, peptide, Peptide, Receptor, Receptors, GPR39, Other, Peptide, Receptors, Other, Peptide, Receptors, Tocris Bioscience

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