NVP CXCR2 20
Potent and selective CXCR2 antagonist (IC50 = 40 nM). Exhibits selectivity for CXCR2 over a panel of 49 other GPCRs. Orally bioavailable.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 319.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||6.26 mL||31.32 mL||62.63 mL|
|2.5 mM||1.25 mL||6.26 mL||12.53 mL|
|5 mM||0.63 mL||3.13 mL||6.26 mL|
|25 mM||0.13 mL||0.63 mL||1.25 mL|
References are publications that support the biological activity of the product.
Porter et al (2014) The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists. Bioorg.Med.Chem.Lett. 24 3285 PMID: 24974342
If you know of a relevant reference for NVP CXCR2 20, please let us know.
View Related Products by Product Action
Keywords: NVP CXCR2 20, NVP CXCR2 20 supplier, NVPCXCR220, chemokine, cxc, receptors, antagonists, antagonism, orally, bioavailable, potent, selective, Chemokine, CXC, Receptors, 5660, Tocris Bioscience
Citations for NVP CXCR2 20
Citations are publications that use Tocris products.
Currently there are no citations for NVP CXCR2 20. Do you know of a great paper that uses NVP CXCR2 20 from Tocris? Please let us know.
Reviews for NVP CXCR2 20
There are currently no reviews for this product. Be the first to review NVP CXCR2 20 and earn rewards!
Have you used NVP CXCR2 20?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.