NPEC-caged-D-AP5

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Cat.No. 4230 - NPEC-caged-D-AP5 | C14H19N2O9P | CAS No. 1416943-27-5
Description: Caged D-AP5 (Cat.No. 0106)
Chemical Name: D-[[1-(2-Nitrophenyl)ethyl]carbamoyl]-2-amino]-5-phosphonopentanoic acid
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

D-AP5 (Cat.No. 0106) caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group. NMDA receptor antagonist.

Technical Data

M. Wt 390.28
Formula C14H19N2O9P
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 1416943-27-5
PubChem ID 90488920
InChI Key RLEANJAZNZWLHC-HCCKASOXSA-N
Smiles O=C(OC(C)C1=CC=CC=C1[N+]([O-])=O)N[C@H](CCCP(O)(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.03 100
water 39.03 100

Preparing Stock Solutions

The following data is based on the product molecular weight 390.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.56 mL 12.81 mL 25.62 mL
5 mM 0.51 mL 2.56 mL 5.12 mL
10 mM 0.26 mL 1.28 mL 2.56 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Murphy et al (1997) Activation of NMDA receptors is necessary for the induction of associative long-term potentiation in area CA1 of the rat hippocampal slice. J.Physiol. 504 379 PMID: 9365912


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Keywords: caged-D-AP5 caged compounds photolysis D-AP5 NMDA antagonist Caged Compounds

Citations for NPEC-caged-D-AP5

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