NPC 15437 dihydrochloride

Discontinued Product

1628 has been discontinued.

View all Protein Kinase C products.
Description: Selective protein kinase C inhibitor
Chemical Name: (2S)-2,6-Diamino-N-[[1-(1-oxotridecyl)-2-piperidinyl]methyl]hexanamide dihydrochloride
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Biological Activity for NPC 15437 dihydrochloride

Highly selective, competitive and reversible inhibitor of protein kinase C (IC50 = 19 mM); interacts at the regulatory domain of the enzyme. May modulate P-glycoprotein in tumor cells in vitro via inhibiton of PKC. Centrally active following systemic administration in vivo.

Technical Data for NPC 15437 dihydrochloride

M. Wt 511.62
Formula C25H50N4O2.2HCl
Storage Desiccate at +4°C
CAS Number 136449-85-9
Smiles O=C(CCCCCCCCCCCC)N1C(CNC([C@H](CCCCN)N)=O)CCCC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for NPC 15437 dihydrochloride

Certificate of Analysis / Product Datasheet
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