Nitrocaramiphen hydrochloride

Pricing Availability Delivery Time Qty
Cat.No. 0469 - Nitrocaramiphen hydrochloride | C18H26N2O4.HCl | CAS No. 98636-73-8
Description: Muscarinic antagonist, M1 > M2
Chemical Name: 2-Diethylaminoethyl 1-(4-nitrophenyl)cyclopentanecarboxylate hydrochloride
Purity: ≥98% (HPLC)

Biological Activity

Muscarinic antagonist with 71-fold selectivity for M1 over M2.

Technical Data

M. Wt 370.88
Formula C18H26N2O4.HCl
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 98636-73-8
PubChem ID 25102587
Smiles O=C(OCCN(CC)CC)C2(CCCC2)C1=CC=C([N+]([O-])=O)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 10 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 370.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.7 mL 13.48 mL 26.96 mL
5 mM 0.54 mL 2.7 mL 5.39 mL
10 mM 0.27 mL 1.35 mL 2.7 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Hudkins et al (1991) Muscarinic receptor binding. Profile of para-sustituted caramiphen analogues. J.Med.Chem 34 2984 PMID: 1920350

Hudkins et al (1993) Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarine M1 receptor selective agents. Eur.J.Pharmacol. 231 485 PMID: 8449241

If you know of a relevant reference for Nitrocaramiphen hydrochloride, please let us know.

View Related Products by Target

View Related Products by Product Action

View all M1 Receptor Antagonists

Keywords: Nitrocaramiphen hydrochloride, supplier, Muscarinic, antagonists, M1, Receptors, Acetylcholine, ACh, M1, Receptors, M1, Receptors, Tocris Bioscience

Citations for Nitrocaramiphen hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Nitrocaramiphen hydrochloride. Do you know of a great paper that uses Nitrocaramiphen hydrochloride from Tocris? If so please let us know.

Reviews for Nitrocaramiphen hydrochloride

There are currently no reviews for this product. Be the first to review Nitrocaramiphen hydrochloride and earn rewards!

Have you used Nitrocaramiphen hydrochloride?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area


GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling

Alzheimer's Poster

Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.


Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Learning & Memory

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.


Schizophrenia Poster

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.