Muscarinic antagonist with 71-fold selectivity for M1 over M2.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 10 mM in water|
References are publications that support the biological activity of the product.
Hudkins et al (1991) Muscarinic receptor binding. Profile of para-sustituted caramiphen analogues. J.Med.Chem 34 2984 PMID: 1920350
Hudkins et al (1993) Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarine M1 receptor selective agents. Eur.J.Pharmacol. 231 485 PMID: 8449241
If you know of a relevant reference for Nitrocaramiphen hydrochloride, please let us know.
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Keywords: Nitrocaramiphen hydrochloride, Nitrocaramiphen hydrochloride supplier, Muscarinic, antagonists, M1, Receptors, Acetylcholine, ACh, 0469, Tocris Bioscience
Citations for Nitrocaramiphen hydrochloride
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.