Neurotensin

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Cat.No. 1909 - Neurotensin | Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu | CAS No. 39379-15-2
Description: Endogenous neurotransmitter and endocrine modulator
Datasheet
Citations
Reviews
Literature

Biological Activity

Brain and gastrointestinal peptide with many central and peripheral functions. Acts as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally, acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular system.

Technical Data

M. Wt 1672.94
Formula C78H121N21O20
Sequence XLYENKPRRPYIL

(Modifications: X = Glp)

Storage Desiccate at -20°C
CAS Number 39379-15-2
PubChem ID 90488724
InChI Key PCJGZPGTCUMMOT-IMEZQUPBSA-N
Smiles CC[C@@H](C)[C@@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 0.70 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Binder et al (2001) Neurotensin and dopamine interactions. Pharmacol.Rev. 53 453 PMID: 11734615

Tyler-McMahon (2000) Neurotensin: peptide for the next millenium. Regul.Pept. 93 125 PMID: 11033059

Vincent et al (1999) Neurotensin and neurotensin receptors. TiPS 20 302 PMID: 10390649


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Keywords: Neurotensin, Neurotensin supplier, Endogenous, neurotransmitter, endocrine, modulators, NT, Receptors, Neurotensin, agonists, 1909, Tocris Bioscience

Citations for Neurotensin

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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