Neuropeptide FF

Pricing Availability   Qty
Cat.No. 3137 - Neuropeptide FF | Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 | CAS No. 99566-27-5
Description: Endogenous NPFF1 and NPFF2 agonist
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects following i.c.v. administration.

Technical Data

M. Wt 1081.28
Formula C54H76N14O10
Sequence FLFQPQRF

(Modifications: Phe-8 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 99566-27-5
PubChem ID 9854861
InChI Key HWYCFZUSOBOBIN-AQJXLSMYSA-N
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Cline et al (2007) Central neuropeptide FF reduces feed consumption and affects hypothalamic chemistry in chicks. Neuropeptides 41 433 PMID: 17936900

Gouarderes et al (2007) Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of[35S]GTPγS binding. Neuropharmacology 52 376 PMID: 17011599


If you know of a relevant reference for Neuropeptide FF, please let us know.

View Related Products by Product Action

View all Neuropeptide FF/AF Receptor Agonists

Keywords: Neuropeptide FF, Neuropeptide FF supplier, Endogenous, NPFF1, NPFF2, agonists, Anti-opioids, NPFFR1, NPFFR2, Receptors, Neuropeptides, FF/AF, NeuropeptideFF, Miscellaneous/Non-selective, Opioids, Neuropeptide, 3137, Tocris Bioscience

Citations for Neuropeptide FF

Citations are publications that use Tocris products.

Currently there are no citations for Neuropeptide FF. Do you know of a great paper that uses Neuropeptide FF from Tocris? Please let us know.

Reviews for Neuropeptide FF

There are currently no reviews for this product. Be the first to review Neuropeptide FF and earn rewards!

Have you used Neuropeptide FF?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing