Neuromedin C (porcine)
Discontinued ProductUnfortunately Neuromedin C (porcine) (Cat. No. 1890) has been withdrawn from sale for commercial reasons.
Mammalian bombesin-like neuropeptide; first isolated from pig spinal cord. Stimulates rat uterine smooth muscle contraction, and gastrin and somatostatin secretion in vitro. Increases blood pressure and pancreatic exocrine secretion in dogs in vivo.
(Modifications: Met-10 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 1120.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.89 mL||4.46 mL||8.93 mL|
|5 mM||0.18 mL||0.89 mL||1.79 mL|
|10 mM||0.09 mL||0.45 mL||0.89 mL|
|50 mM||0.02 mL||0.09 mL||0.18 mL|
References are publications that support the products' biological activity.
Hosotani et al (1985) Effect of synthetic neuromedin C, a decapeptide of gastrin-releasing peptide (GRP[18-27]), on blood flow and exocrine secretion of the pancreas in dogs. Life Sci. 36 2429 PMID: 3892215
Madaus et al (1989) Effect of gastrin-releasing peptide (GRP1-27), neuromedin-C (GRP18-27), and neuromedin-B on gastrin and somatostatin secretion from the rat stomach. Z.Gastroenterol. 27 449 PMID: 2573979
Minamino et al (1984) Neuromedin C: a bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 119 14 PMID: 6546686
Keywords: Neuromedin C (porcine), supplier, Mammalian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, NeuromedinC, (porcine), GRP, (18-27), Bombesin, Receptors, Bombesin, Receptors, Tocris Bioscience
Citations for Neuromedin C (porcine)
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Currently there are no citations for Neuromedin C (porcine).
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Literature in this Area
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.