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Submit ReviewNeuromedin C (porcine)
Discontinued Product
Neuromedin C (porcine) (Cat. No. 1890) has been withdrawn from sale for commercial reasons.
Description: Mammalian bombesin-like peptide
Alternative Names: GRP (18-27)
Biological Activity for Neuromedin C (porcine)
Mammalian bombesin-like neuropeptide; first isolated from pig spinal cord. Stimulates rat uterine smooth muscle contraction, and gastrin and somatostatin secretion in vitro. Increases blood pressure and pancreatic exocrine secretion in dogs in vivo.
Technical Data for Neuromedin C (porcine)
| M. Wt | 1120.29 |
| Formula | C50H73N17O11S |
| Sequence |
GNHWAVGHLM (Modifications: Met-10 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 81608-30-2 |
| Smiles | [H]NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Neuromedin C (porcine)
References for Neuromedin C (porcine)
References are publications that support the biological activity of the product.
Hosotani et al (1985) Effect of synthetic neuromedin C, a decapeptide of gastrin-releasing peptide (GRP[18-27]), on blood flow and exocrine secretion of the pancreas in dogs. Life Sci. 36 2429 PMID: 3892215
Madaus et al (1989) Effect of gastrin-releasing peptide (GRP1-27), neuromedin-C (GRP18-27), and neuromedin-B on gastrin and somatostatin secretion from the rat stomach. Z.Gastroenterol. 27 449 PMID: 2573979
Minamino et al (1984) Neuromedin C: a bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 119 14 PMID: 6546686
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Citations for Neuromedin C (porcine)
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