Neuromedin C (porcine)

Discontinued Product

Unfortunately Neuromedin C (porcine) (Cat. No. 1890) has been withdrawn from sale for commercial reasons.
Cat.No. 1890 - Neuromedin C (porcine) | Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 | CAS No. 81608-30-2
Description: Mammalian bombesin-like peptide
Alternative Names: GRP (18-27)

Biological Activity

Mammalian bombesin-like neuropeptide; first isolated from pig spinal cord. Stimulates rat uterine smooth muscle contraction, and gastrin and somatostatin secretion in vitro. Increases blood pressure and pancreatic exocrine secretion in dogs in vivo.

Technical Data

M. Wt 1120.29
Formula C50H73N17O11S

(Modifications: Met-10 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 81608-30-2
Smiles [H]NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 1120.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.89 mL 4.46 mL 8.93 mL
5 mM 0.18 mL 0.89 mL 1.79 mL
10 mM 0.09 mL 0.45 mL 0.89 mL
50 mM 0.02 mL 0.09 mL 0.18 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Hosotani et al (1985) Effect of synthetic neuromedin C, a decapeptide of gastrin-releasing peptide (GRP[18-27]), on blood flow and exocrine secretion of the pancreas in dogs. Life Sci. 36 2429 PMID: 3892215

Madaus et al (1989) Effect of gastrin-releasing peptide (GRP1-27), neuromedin-C (GRP18-27), and neuromedin-B on gastrin and somatostatin secretion from the rat stomach. Z.Gastroenterol. 27 449 PMID: 2573979

Minamino et al (1984) Neuromedin C: a bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 119 14 PMID: 6546686

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