Endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).
(Modifications: Met-10 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 0.80 mg/ml in water|
References are publications that support the biological activity of the product.
Laufer et al (1985) Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. Proc.Natl.Acad.Sci.U.S.A. 82 7444 PMID: 2414777
Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144
Wang et al (2001) Neurokinin B potentiates ATP-activated currents in rat DRG neurons. Brain Res. 923 157 PMID: 11743983
If you know of a relevant reference for Neurokinin B (human, porcine), please let us know.
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Citations for Neurokinin B (human, porcine)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.