Neurokinin B (human, porcine)

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Cat.No. 1582 - Neurokinin B (human, porcine) | Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 | CAS No. 86933-75-7
Description: Endogenous tachykinin peptide
Alternative Names: NKB
Datasheet
Citations
Reviews
Literature

Biological Activity

Endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).

Technical Data

M. Wt 1210.43
Formula C55H79N13O14S2
Sequence DMHDFFVGLM

(Modifications: Met-10 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 86933-75-7
PubChem ID 5311312
InChI Key NHXYSAFTNPANFK-HDMCBQFHSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 0.80 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Laufer et al (1985) Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. Proc.Natl.Acad.Sci.U.S.A. 82 7444 PMID: 2414777

Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144

Wang et al (2001) Neurokinin B potentiates ATP-activated currents in rat DRG neurons. Brain Res. 923 157 PMID: 11743983


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Citations for Neurokinin B (human, porcine)

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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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