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Neurokinin B (human, porcine) is an endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).
(Modifications: Met-10 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in DMSO|
References are publications that support the biological activity of the product.
Laufer et al (1985) Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. Proc.Natl.Acad.Sci.U.S.A. 82 7444 PMID: 2414777
Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144
Wang et al (2001) Neurokinin B potentiates ATP-activated currents in rat DRG neurons. Brain Res. 923 157 PMID: 11743983
If you know of a relevant reference for Neurokinin B (human, porcine), please let us know.
Keywords: Neurokinin B (human, porcine), Neurokinin B (human, porcine) supplier, Endogenous, tachykinin, peptide, Non-Selective, Neurokinin, Receptors, NeurokininB, (human, porcine), NKB, Other, Tachykinin, 1582, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Neurokinin B (human, porcine) include:
Weems et al (2018) Evidence That Dynorphin Acts Upon KNDy and GnRH Neurons During GnRH Pulse Termination in the Ewe. Endocrinology 159 3187 PMID: 30016419
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.