Neurokinin A (porcine)

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Cat.No. 1152 - Neurokinin A (porcine) | His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 | CAS No. 86933-74-6
Description: Endogenous tachykinin peptide
Alternative Names: NKA
Datasheet
Citations (1)
Reviews
Literature (5)

Biological Activity

Endogenous tachykinin peptide; more potent bronchoconstrictor than Substance P.

Technical Data

M. Wt 1133.3
Formula C50H80N14O14S
Sequence HKTDSFVGLM

(Modifications: Met-10 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 86933-74-6
PubChem ID 5311311
InChI Key HEAUFJZALFKPBA-JPQUDPSNSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Lippe et al (1997) Neurokinin A-induced vasoconstriction and muscular contraction in the rat isolated stomach: mediation by distinct and unusual neurokinin A2 receptors. J.Pharmacol.Exp.Ther. 281 1294 PMID: 9190865

Nawa et al (1983) Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor. Nature 306 32 PMID: 6195531

Sherwood et al (1997) Bronchoconstrictor and respiratory effects of neurokinin A in dogs. J.Pharmacol.Exp.Ther. 283 788 PMID: 9353399


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Keywords: Neurokinin A (porcine), Neurokinin A (porcine) supplier, Endogenous, tachykinin, peptide, Non-Selective, Neurokinin, Receptors, agonists, NeurokininA, NKA, Other, Tachykinin, 1152, Tocris Bioscience

1 Citation for Neurokinin A (porcine)

Citations are publications that use Tocris products. Selected citations for Neurokinin A (porcine) include:

Gutierrez and Boada (2019) Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int 18 216 PMID: 30598641


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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