|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 474.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.11 mL||10.54 mL||21.08 mL|
|5 mM||0.42 mL||2.11 mL||4.22 mL|
|10 mM||0.21 mL||1.05 mL||2.11 mL|
|50 mM||0.04 mL||0.21 mL||0.42 mL|
References are publications that support the products' biological activity.
Douris (1992) Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat. Eur.J.Pharmacol. 219 105 PMID: 1397037
Glennon et al (1988) Arylpiperazine derivatives as high affinity 5-HT1A serotonin ligands. J.Med.Chem. 31 1968 PMID: 3172131
Williams and Glennon (1988) NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Eur.J.Pharmacol. 154 339 PMID: 2976673
If you know of a relevant reference for NAN-190 hydrobromide, please let us know.
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Keywords: NAN-190 hydrobromide, supplier, 5-HT1A, antagonists, Serotonin, Receptors, 5-HT1, NAN190, 5-HT1A, Receptors, 5-HT1A, Receptors, Tocris Bioscience
2 Citations for NAN-190 hydrobromide
Citations are publications that use Tocris products. Selected citations for NAN-190 hydrobromide include:
Demarque and (2010) Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior. Neuron 67 321 PMID: 20670838
Pagano et al (2008) Gαo/i-stimulated proteosomal degradation of RGS20: a mechanism for temporal integration of Gs and Gi pathways. Physiol Behav 20 1190 PMID: 18407463
Do you know of a great paper that uses NAN-190 hydrobromide from Tocris? If so please let us know.
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