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Naloxone 3-glucuronide carbonic acid salt
Naloxone conjugate. Following oral administration induces delayed diarrhea, as well as milder and delayed withdrawal behavior and tail skin temperature (TST) response compared with naloxone in morphine-dependent rats.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 565.52. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.77 mL||8.84 mL||17.68 mL|
|5 mM||0.35 mL||1.77 mL||3.54 mL|
|10 mM||0.18 mL||0.88 mL||1.77 mL|
|50 mM||0.04 mL||0.18 mL||0.35 mL|
References are publications that support the biological activity of the product.
Simpkins et al (1988) Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J.Pharmacol.Exp.Ther. 244 195 PMID: 3335997
If you know of a relevant reference for Naloxone 3-glucuronide carbonic acid salt, please let us know.
Keywords: Naloxone 3-glucuronide carbonic acid salt, Naloxone 3-glucuronide carbonic acid salt supplier, constipation, opioids, diarrhea, narcotics, glucuronide, conjugates, TST, tail, skin, temperature, Miscellaneous/Non-selective, Opioids, 5684, Tocris Bioscience
Citations for Naloxone 3-glucuronide carbonic acid salt
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
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