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Submit ReviewN-Desisopropylpropranolol hydrochloride
Discontinued Product
N-Desisopropylpropranolol hydrochloride (Cat. No. 0848) has been withdrawn from sale for commercial reasons.
Description: Propranolol metabolite
Chemical Name: 1-Amino-3-(1-naphthalenyloxy)propan-2-ol hydrochloride
Biological Activity
Metabolite of propranolol.
Technical Data
| M. Wt | 253.73 |
| Storage | Store at RT |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References
References are publications that support the biological activity of the product.
Ishida et al (1992) Enzymatic basis for the non-linearity of hepatic elimination of propra. in the isolated perfused rat liver. Biochem.Pharmacol. 44 2281 PMID: 1472093
Masubachi et al (1993) Substrate stereoselectivity and enantiomer/enantiomer interaction in propra. metabolism in the rat liver microsomes. Biochem.Pharmacol. 46 1759 PMID: 8250961
Steiner et al (1992) Induction of propanolol metabolism in the Hep G2 human hepatoma cell line. J.Pharm.Pharmacol. 44 611 PMID: 1357146
Bourne (1981) The metabolism of β-adrenoceptor blocking drugs. Drug Metabolism 6 77
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Citations for N-Desisopropylpropranolol hydrochloride
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.