Discontinued ProductUnfortunately N-Desisopropylpropranolol hydrochloride (Cat. No. 0848) has been withdrawn from sale for commercial reasons.
Metabolite of propranolol.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
References are publications that support the products' biological activity.
Ishida et al (1992) Enzymatic basis for the non-linearity of hepatic elimination of propranolol in the isolated perfused rat liver. Biochem.Pharmacol. 44 2281 PMID: 1472093
Masubachi et al (1993) Substrate stereoselectivity and enantiomer/enantiomer interaction in propranolol metabolism in the rat liver microsomes. Biochem.Pharmacol. 46 1759 PMID: 8250961
Steiner et al (1992) Induction of propanolol metabolism in the Hep G2 human hepatoma cell line. J.Pharm.Pharmacol. 44 611 PMID: 1357146
Keywords: N-Desisopropylpropranolol hydrochloride, supplier, Non-selective, Adrenergic, Beta, Receptors, Non-selective, Adrenergic, Beta, Receptors, Tocris Bioscience
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.