N-Desisopropylpropranolol hydrochloride

Discontinued Product

Unfortunately N-Desisopropylpropranolol hydrochloride (Cat. No. 0848) has been withdrawn from sale for commercial reasons.
Cat.No. 0848 - N-Desisopropylpropranolol hydrochloride
Description: Propranolol metabolite
Chemical Name: 1-Amino-3-(1-naphthalenyloxy)propan-2-ol hydrochloride
Datasheet
Citations
Reviews
Literature

Biological Activity

Metabolite of propranolol.

Technical Data

M. Wt 253.73
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 253.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.94 mL 19.71 mL 39.41 mL
5 mM 0.79 mL 3.94 mL 7.88 mL
10 mM 0.39 mL 1.97 mL 3.94 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet

References

References are publications that support the products' biological activity.

Ishida et al (1992) Enzymatic basis for the non-linearity of hepatic elimination of propranolol in the isolated perfused rat liver. Biochem.Pharmacol. 44 2281 PMID: 1472093

Masubachi et al (1993) Substrate stereoselectivity and enantiomer/enantiomer interaction in propranolol metabolism in the rat liver microsomes. Biochem.Pharmacol. 46 1759 PMID: 8250961

Steiner et al (1992) Induction of propanolol metabolism in the Hep G2 human hepatoma cell line. J.Pharm.Pharmacol. 44 611 PMID: 1357146

Bourne (1981) The metabolism of β-adrenoceptor blocking drugs. Drug Metabolism 6 77 PMID:

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Citations for N-Desisopropylpropranolol hydrochloride

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Currently there are no citations for N-Desisopropylpropranolol hydrochloride.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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