Discontinued ProductUnfortunately N-Butyl-N-ethyl-2-(1-naphthyloxy)ethanamine hydrochloride (Cat. No. 0406) has been withdrawn from sale for commercial reasons.
Selective 5-HT1A ligand, produced by systematic variation of the structure of propranolol.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 307.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.25 mL||16.24 mL||32.48 mL|
|5 mM||0.65 mL||3.25 mL||6.5 mL|
|10 mM||0.32 mL||1.62 mL||3.25 mL|
|50 mM||0.06 mL||0.32 mL||0.65 mL|
References are publications that support the products' biological activity.
Pierson et al (1989) Design and synthesis of propanolol analogues as serotonergic agents. J.Med.Chem. 32 859 PMID: 2539480
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Keywords: N-Butyl-N-ethyl-2-(1-naphthyloxy)ethanamine hydrochloride, supplier, 5-HT1A, Receptors, 5-HT1A, Receptors, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.